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Click virus name to view the detail mutation information of each virus
The search result of mutation sites in HBV P region
ID
PMID
Mutation
Gene/Protein/Region
Description
Detail
1
33446224
V173L
RT
D
G
R
S
CI
C
View
2
33446224
L180M
RT
D
G
R
S
CI
C
View
3
33446224
S202I
RT
D
G
R
S
CI
C
View
4
33446224
M204V
RT
D
G
R
S
CI
C
View
5
33446224
M204I
RT
D
G
R
S
CI
C
View
6
19065672
A181T
RT
D
G
S
CI
C
View
7
19065672
A181V
RT
D
G
S
CI
C
View
8
19065672
N236T
RT
D
G
S
CI
C
View
9
20119580
A181T
RT
D
G
R
CI
C
View
10
20119580
A181V
RT
D
G
R
CI
C
View
11
23710315
A181V
RT
D
G
R
CI
C
View
12
23710315
S202G
RT
D
G
R
CI
C
View
13
24637457
L80*
RT
D
G
R
S
C
View
14
24637457
I169N
RT
D
G
R
S
C
View
15
24637457
V173L
RT
D
G
R
S
C
View
16
24637457
L180*
RT
D
G
R
S
C
View
17
24637457
A181G
RT
D
G
R
S
C
View
18
24637457
S202I
RT
D
G
R
S
C
View
19
24637457
M204V
RT
D
G
R
S
C
View
20
24637457
Q215S
RT
D
G
R
S
C
View
21
24637457
I233V
RT
D
G
R
S
C
View
22
24637457
N236I
RT
D
G
R
S
C
View
23
24637457
M250V
RT
D
G
R
S
C
View
24
25503289
C400A
RT
G
R
S
I
C
View
25
25503289
T472G
RT
G
R
S
I
C
View
26
25503289
A533C
RT
G
R
S
I
C
View
27
25503289
A533T
RT
G
R
S
I
C
View
28
25503289
A793T
RT
G
R
S
I
C
View
29
25503289
C823A
RT
G
R
S
I
C
View
30
25503289
A871C
RT
G
R
S
I
C
View
31
25503289
T895A
RT
G
R
S
I
C
View
32
25503289
T918A
RT
G
R
S
I
C
View
33
25503289
T926G
RT
G
R
S
I
C
View
34
25503289
T926A
RT
G
R
S
I
C
View
35
25503289
G950A
RT
G
R
S
I
C
View
36
25503289
A965C
RT
G
R
S
I
C
View
37
25503289
T1055A
RT
G
R
S
I
C
View
38
25503289
A853C
RT
G
R
S
I
C
View
39
25503289
C888A
RT
G
R
S
I
C
View
40
25503289
A906C
RT
G
R
S
I
C
View
41
25503289
T907A
RT
G
R
S
I
C
View
42
25503289
T907C
RT
G
R
S
I
C
View
43
25503289
G909A
RT
G
R
S
I
C
View
44
25503289
G969A
RT
G
R
S
I
C
View
45
25503289
C987G
RT
G
R
S
I
C
View
46
25503289
C987T
RT
G
R
S
I
C
View
47
25503289
C987A
RT
G
R
S
I
C
View
48
25503289
G852A
RT
G
R
S
I
C
View
49
25503289
C406T
RT
G
R
S
I
C
View
50
25503289
A436G
RT
G
R
S
I
C
View
51
25503289
G779T
RT
G
R
S
I
C
View
52
25503289
A886G
RT
G
R
S
I
C
View
53
25503289
A952G
RT
G
R
S
I
C
View
54
25503289
C885T
RT
G
R
S
I
C
View
55
25503289
A903G
RT
G
R
S
I
C
View
56
25503289
G933A
RT
G
R
S
I
C
View
57
25503289
A987C
RT
G
R
S
I
C
View
58
25503289
A994C
RT
G
R
S
I
C
View
59
25503289
L91I
RT
G
R
S
I
C
View
60
25503289
H94I
RT
G
R
S
I
C
View
61
25503289
R110G
RT
G
R
S
I
C
View
62
25503289
L115V
RT
G
R
S
I
C
View
63
25503289
F122I
RT
G
R
S
I
C
View
64
25503289
H124Y
RT
G
R
S
I
C
View
65
25503289
Y135S
RT
G
R
S
I
C
View
66
25503289
Y135F
RT
G
R
S
I
C
View
67
25503289
S137T
RT
G
R
S
I
C
View
68
25503289
L145M
RT
G
R
S
I
C
View
69
25503289
R153K
RT
G
R
S
I
C
View
70
25503289
R153Q
RT
G
R
S
I
C
View
71
25503289
S219P
RT
G
R
S
I
C
View
72
25503289
F221Y
RT
G
R
S
I
C
View
73
25503289
T222S
RT
G
R
S
I
C
View
74
25503289
P237T
RT
G
R
S
I
C
View
75
25503289
N248H
RT
G
R
S
I
C
View
76
25503289
C256S
RT
G
R
S
I
C
View
77
25503289
D263E
RT
G
R
S
I
C
View
78
25503289
I266K
RT
G
R
S
I
C
View
79
25503289
R274K
RT
G
R
S
I
C
View
80
25503289
N279T
RT
G
R
S
I
C
View
81
25503289
M309K
RT
G
R
S
I
C
View
82
25503289
V142V
RT
G
R
S
I
C
View
83
25503289
L168L
RT
G
R
S
I
C
View
84
25503289
H117H
RT
G
R
S
I
C
View
85
25503289
Q215Q
RT
G
R
S
I
C
View
86
25503289
R242R
RT
G
R
S
I
C
View
87
25503289
V253V
RT
G
R
S
I
C
View
88
25503289
S259S
RT
G
R
S
I
C
View
89
25503289
L260L
RT
G
R
S
I
C
View
90
25503289
R280R
RT
G
R
S
I
C
View
91
25503289
V286V
RT
G
R
S
I
C
View
92
25503289
Y135H
RT
G
R
S
I
C
View
93
25503289
I163V
RT
G
R
S
I
C
View
94
25503289
S213T
RT
G
R
S
I
C
View
95
25503289
V214D
RT
G
R
S
I
C
View
96
25503289
H134H
RT
G
R
S
I
C
View
97
25503289
V208V
RT
G
R
S
I
C
View
98
25503289
A211A
RT
G
R
S
I
C
View
99
25503289
K241K
RT
G
R
S
I
C
View
100
25503289
L93F
RT
G
R
S
I
C
View
101
25503289
I103V
RT
G
R
S
I
C
View
102
25503289
L217R
RT
G
R
S
I
C
View
103
25503289
I253V
RT
G
R
S
I
C
View
104
25503289
K275E
RT
G
R
S
I
C
View
105
25503289
Y252Y
RT
G
R
S
I
C
View
106
25503289
G258G
RT
G
R
S
I
C
View
107
25503289
K268K
RT
G
R
S
I
C
View
108
25503289
R289R
RT
G
R
S
I
C
View
109
28500726
A194T
RT
D
G
R
S
C
View
110
28500726
L180M
RT
D
G
R
S
C
View
111
28500726
L80I
RT
D
G
R
S
C
View
112
28500726
L80V
RT
D
G
R
S
C
View
113
28500726
M204I
RT
D
G
R
S
C
View
114
28500726
M204V
RT
D
G
R
S
C
View
115
31248149
H271C
RT
D
G
R
CI
C
View
116
31248149
I121N
RT
D
G
R
CI
C
View
117
31248149
I163V
RT
D
G
R
CI
C
View
118
31248149
K270R
RT
D
G
R
CI
C
View
119
31248149
L140P
RT
D
G
R
CI
C
View
120
31248149
L217R
RT
D
G
R
CI
C
View
121
31248149
L220I
RT
D
G
R
CI
C
View
122
31248149
M129L
RT
D
G
R
CI
C
View
123
31248149
N238H
RT
D
G
R
CI
C
View
124
31248149
P237H
RT
D
G
R
CI
C
View
125
31248149
R110G
RT
D
G
R
CI
C
View
126
31248149
R138E
RT
D
G
R
CI
C
View
127
31248149
R138K
RT
D
G
R
CI
C
View
128
31248149
R242K
RT
D
G
R
CI
C
View
129
31248149
R280S
RT
D
G
R
CI
C
View
130
31248149
S117C
RT
D
G
R
CI
C
View
131
31248149
S117Y
RT
D
G
R
CI
C
View
132
31248149
T128I
RT
D
G
R
CI
C
View
133
31248149
T128S
RT
D
G
R
CI
C
View
134
31248149
T225I
RT
D
G
R
CI
C
View
135
31248149
T259S
RT
D
G
R
CI
C
View
136
31248149
V142A
RT
D
G
R
CI
C
View
137
31248149
V278I
RT
D
G
R
CI
C
View
138
31248149
W153R
RT
D
G
R
CI
C
View
139
31248149
Y126H
RT
D
G
R
CI
C
View
140
31248149
N122H
RT
D
G
R
CI
C
View
141
31248149
P109S
RT
D
G
R
CI
C
View
142
31248149
S105T
RT
D
G
R
CI
C
View
143
31248149
N76D
RT
D
G
R
CI
C
View
144
31248149
V266R
RT
D
G
R
CI
C
View
145
31248149
V253I
RT
D
G
R
CI
C
View
146
31248149
V266I
RT
D
G
R
CI
C
View
147
31248149
L129M
RT
D
G
R
CI
C
View
148
31248149
Q125E
RT
D
G
R
CI
C
View
149
31248149
H271Y
RT
D
G
R
CI
C
View
150
32216026
L180M
RT
D
G
R
S
C
View
151
32216026
M204V
RT
D
G
R
S
C
View
152
32216026
T184A
RT
D
G
R
S
C
View
153
32216026
T184L
RT
D
G
R
S
C
View
154
32216026
S202G
RT
D
G
R
S
C
View
155
32216026
M250V
RT
D
G
R
S
C
View
156
32216026
I169T
RT
D
G
R
S
C
View
157
33381105
L180M
RT
D
G
R
S
C
View
158
33381105
M204V
RT
D
G
R
S
C
View
159
33381105
A181T
RT
D
G
R
S
C
View
160
33381105
A181V
RT
D
G
R
S
C
View
161
33381105
T184G
RT
D
G
R
S
C
View
162
33381105
T184S
RT
D
G
R
S
C
View
163
33381105
S202G
RT
D
G
R
S
C
View
164
33381105
S202I
RT
D
G
R
S
C
View
165
33381105
M204I
RT
D
G
R
S
C
View
166
33381105
N236T
RT
D
G
R
S
C
View
167
33381105
M250V
RT
D
G
R
S
C
View
168
33571155
A181V
RT
D
G
S
CI
C
View
169
33571155
T184A
RT
D
G
S
CI
C
View
170
33571155
S202G
RT
D
G
S
CI
C
View
171
33571155
M204V
RT
D
G
S
CI
C
View
172
33571155
L180M
RT
D
G
S
CI
C
View
173
33836203
Y124H
RT
G
R
S
CI
C
View
174
15953865
M204I
RT
D
G
R
C
View
175
16789011
L180M
RT
D
G
R
C
View
176
16789011
M204I
RT
D
G
R
C
View
177
16789011
M204V
RT
D
G
R
C
View
178
17506609
L180M
RT
D
G
S
C
View
179
17506609
M204V
RT
D
G
S
C
View
180
17506609
V173L
RT
D
G
S
C
View
181
18036224
L180M
RT
D
G
S
C
View
182
18036224
M204V
RT
D
G
S
C
View
183
18036224
V173L
RT
D
G
S
C
View
184
18171343
L180M
RT
D
G
S
C
View
185
18171343
M204I
RT
D
G
S
C
View
186
18171343
M204V
RT
D
G
S
C
View
187
18171343
S117Y
RT
D
G
S
C
View
188
18171343
V142A
RT
D
G
S
C
View
189
18171343
S117C
RT
D
G
S
C
View
190
18171343
G743C
RT
D
G
S
C
View
191
18171343
A741G
RT
D
G
S
C
View
192
18211717
L180M
RT
D
G
S
C
View
193
18211717
M204V
RT
D
G
S
C
View
194
18211717
M204I
RT
D
G
S
C
View
195
18211717
L180I
RT
D
G
S
C
View
196
18713056
L180M
RT
D
G
R
S
View
197
18713056
M204I
RT
D
G
R
S
View
198
18713056
M204V
RT
D
G
R
S
View
199
18713056
V173L
RT
D
G
R
S
View
200
18713056
L82M
RT
D
G
R
S
View
201
18713056
L428M
P
D
G
R
S
View
202
18713056
C619T
P
D
G
R
S
View
203
18713056
T739G
P
D
G
R
S
View
204
18713056
G741T
P
D
G
R
S
View
205
18713056
T2830A
P
D
G
R
S
View
206
18713056
T565C
P
D
G
R
S
View
207
18713056
A646T
P
D
G
R
S
View
208
18713056
A646C
P
D
G
R
S
View
209
18713056
V519L
P
D
G
R
S
View
210
18713056
C853A
P
D
G
R
S
View
211
18713056
T667A
P
D
G
R
S
View
212
18713056
L528M
P
D
G
R
S
View
213
18713056
T1568C
P
D
G
R
S
View
214
18713056
L826P
P
D
G
R
S
View
215
18713056
N118K
RT
D
G
R
S
View
216
18713056
V184D
RT
D
G
R
S
View
217
19041149
N139K
RT
D
G
I
C
View
218
19125938
L180M
RT
D
G
S
C
View
219
19125938
M204I
RT
D
G
S
C
View
220
19125938
M204V
RT
D
G
S
C
View
221
19125938
T184L
RT
D
G
S
C
View
222
19272629
T473C
RT
G
R
CI
C
View
223
19272629
L461S
RT
G
R
CI
C
View
224
19272629
Y470N
RT
G
R
CI
C
View
225
19889143
V112I
RT
G
R
S
C
View
226
19889143
Q101L
P
G
R
S
C
View
227
19889143
L112P
P
G
R
S
C
View
228
19889143
Q150R
P
G
R
S
C
View
229
19889143
H164N
P
G
R
S
C
View
230
19889143
F19S
P
G
R
S
C
View
231
19889143
R44*
P
G
R
S
C
View
232
19889143
R44K
P
G
R
S
C
View
233
19889143
Q48R
P
G
R
S
C
View
234
19889143
S102P
P
G
R
S
C
View
235
19889143
E105G
P
G
R
S
C
View
236
19889143
S109F
P
G
R
S
C
View
237
19889143
R29L
P
G
R
S
C
View
238
19889143
I103T
RT
G
R
S
C
View
239
19889143
C136Y
RT
G
R
S
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C798Y
P
G
S
C
View
1893
32532295
H136YN
P
G
S
C
View
1894
32532295
P249S
P
G
S
C
View
1895
32532295
T251A
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S
C
View
1896
32532295
S268G
P
G
S
C
View
1897
32532295
L613QH
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G
S
C
View
1898
32532295
S272TN
P
G
S
C
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1899
32532295
T1485A
P
G
S
C
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1900
32545313
L180M
RT
D
S
C
View
1901
32545313
A181T
RT
D
S
C
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1902
32545313
M204I
RT
D
S
C
View
1903
32545313
M204V
RT
D
S
C
View
1904
32569703
A181S
RT
D
G
C
View
1905
32569703
T184I
RT
D
G
C
View
1906
32569703
M204I
RT
D
G
C
View
1907
32569703
M204V
RT
D
G
C
View
1908
32569703
M250V
RT
D
G
C
View
1909
32569703
A181T
RT
D
G
C
View
1910
32569703
L180M
RT
D
G
C
View
1911
32569703
A181V
RT
D
G
C
View
1912
32569703
A181C
RT
D
G
C
View
1913
32569703
N236T
RT
D
G
C
View
1914
32569703
T184G
RT
D
G
C
View
1915
32569703
T184V
RT
D
G
C
View
1916
32569703
T184A
RT
D
G
C
View
1917
32569703
T184F
RT
D
G
C
View
1918
32569703
T184S
RT
D
G
C
View
1919
32569703
S202G
RT
D
G
C
View
1920
32569703
T184M
RT
D
G
C
View
1921
32735901
V173L
RT
D
G
C
View
1922
32735901
M204I
RT
D
G
C
View
1923
32735901
M204V
RT
D
G
C
View
1924
32735901
L180M
RT
D
G
C
View
1925
32735901
S202G
RT
D
G
C
View
1926
33124952
L229V
RT
D
S
C
View
1927
33124952
V191I
RT
G
S
C
View
1928
33124952
A181T
RT
G
S
C
View
1929
33124952
A181V
RT
G
S
C
View
1930
33124952
M204V
RT
D
S
C
View
1931
33124952
L180M
RT
D
S
C
View
1932
33124952
M204I
RT
D
S
C
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1933
33124952
L229M
RT
D
S
C
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1934
33124952
L229F
RT
D
S
C
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1935
33124952
G741A
RT
D
S
C
View
1936
33187530
N122P
RT
R
S
C
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1937
33187530
S109P
RT
R
S
C
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1938
33187530
N122H
RT
R
S
C
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1939
33187530
S202R
RT
R
S
C
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1940
33187530
S202P
RT
R
S
C
View
1941
33187530
M204R
RT
R
S
C
View
1942
33211768
I169T
RT
D
G
C
View
1943
33211768
V173L
RT
D
G
C
View
1944
33211768
A181T
RT
D
G
C
View
1945
33211768
T184A
RT
D
G
C
View
1946
33211768
T184G
RT
D
G
C
View
1947
33211768
T184C
RT
D
G
C
View
1948
33211768
A194T
RT
D
G
C
View
1949
33211768
S202I
RT
D
G
C
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1950
33211768
M250L
RT
D
G
C
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1951
33211768
M250V
RT
D
G
C
View
1952
33357228
M204I
RT
D
G
C
View
1953
33462964
D134N
RT
G
R
C
View
1954
33462964
D134S
RT
G
R
C
View
1955
33947693
T1165C
P
R
CI
C
View
1956
33947693
A2721G
P
R
CI
C
View
1957
33947693
T2666C
P
R
CI
C
View
1958
33947693
A2627T
P
R
CI
C
View
1959
33947693
A2633G
P
R
CI
C
View
1960
33947693
G2771T
P
R
CI
C
View
1961
33947693
A841C
P
R
CI
C
View
1962
33947693
A951G
P
R
CI
C
View
1963
33947693
G957T
P
R
CI
C
View
1964
33947693
A1062G
P
R
CI
C
View
1965
33947693
T1078G
P
R
CI
C
View
1966
33947693
C2583G
P
R
CI
C
View
1967
33947693
A2590T
P
R
CI
C
View
1968
33947693
A2699G
P
R
CI
C
View
1969
33947693
T2708G
P
R
CI
C
View
1970
33947693
C2771T
P
R
CI
C
View
1971
33947693
A2867C
P
R
CI
C
View
1972
33947693
C2875A
P
R
CI
C
View
1973
33947693
C3026T
P
R
CI
C
View
1974
33947693
G3210A
P
R
CI
C
View
1975
10385663
A532S
P
D
G
View
1976
10385663
F496Y
P
D
G
View
1977
10502255
L428M
P
G
C
View
1978
10534721
V69A
RT
G
C
View
1979
10534721
H83R
RT
G
C
View
1980
10534721
Y136H
RT
G
C
View
1981
10534721
T240A
RT
G
C
View
1982
10534721
R242K
RT
G
C
View
1983
10534721
R255T
RT
G
C
View
1984
10534721
N256H
RT
G
C
View
1985
10534721
V257R
RT
G
C
View
1986
10534721
Y275D
RT
G
C
View
1987
10534721
S285A
RT
G
C
View
1988
10534721
I498T
P
G
C
View
1989
10534721
I601R
P
G
C
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1990
10534721
V613I
P
G
C
View
1991
10534721
I617R
P
G
C
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1992
10534721
P645S
P
G
C
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1993
10534721
M699I
P
G
C
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1994
10534721
L709P
P
G
C
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1995
10534721
R711P
P
G
C
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1996
10534721
L712V
P
G
C
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1997
10655370
L528M
P
D
G
View
1998
10655370
L555I
P
D
G
View
1999
10762559
L528M
P
D
CI
View
2000
10762559
M552I
RT
D
CI
View
2001
11020004
L528M
P
D
R
View
2002
11020004
M552I
P
D
R
View
2003
11020004
M552V
P
D
R
View
2004
11020004
V555I
P
D
R
View
2005
11020004
L552M
P
D
R
View
2006
11050059
Q474H
P
G
CI
View
2007
11502520
L526M
P
D
G
View
2008
11502520
M550I
P
D
G
View
2009
11502520
M550V
P
D
G
View
2010
11792996
M550I
P
D
C
View
2011
11792996
M550V
P
D
C
View
2012
11792996
L526M
P
D
C
View
2013
12445424
L526M
P
D
C
View
2014
12445424
M550I
P
D
C
View
2015
12445424
M550V
P
D
C
View
2016
12448687
M552V
P
G
C
View
2017
12448687
L528M
P
G
C
View
2018
12448687
M550V
P
G
C
View
2019
12448687
L526M
P
G
C
View
2020
12448687
M539V
P
G
C
View
2021
12448687
L515M
P
G
C
View
2022
12448687
M549V
P
G
C
View
2023
12448687
L525M
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G
C
View
2024
12500185
L180M
RT
D
G
View
2025
12500185
M204I
RT
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G
View
2026
12500185
M204V
RT
D
G
View
2027
12757503
H491P
P
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S
View
2028
12757503
V438F
P
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S
View
2029
12757503
L492P
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View
2030
12757503
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2031
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2032
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S
View
2033
12757503
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S
View
2034
12757503
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P
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2035
12757503
V549A
P
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S
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2036
12757503
Q550H
P
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2037
12780567
L180M
RT
D
C
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2038
12780567
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RT
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2039
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2040
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2041
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2042
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2043
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2044
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2045
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2046
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2047
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2048
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2049
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2050
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2051
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2052
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2053
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2054
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2055
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2056
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2057
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2058
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2059
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2060
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2061
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2062
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2063
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2064
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2065
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2066
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2067
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2068
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2069
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2070
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2071
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2072
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2073
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2074
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2075
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2076
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2077
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2078
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2079
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2080
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2081
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2082
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2083
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2084
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2085
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2086
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2087
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2088
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2089
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2090
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2091
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2092
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2093
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2094
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2095
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I
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2096
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I
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2097
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I
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2098
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2099
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2100
12870011
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2101
12891527
N236T
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2102
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2103
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View
2104
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2105
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2106
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2107
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2108
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2109
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2110
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2111
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2112
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2113
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2114
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2115
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2116
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2117
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2118
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2119
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2120
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2121
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2122
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2123
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2124
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2125
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2126
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2127
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2128
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2129
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2131
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2133
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2140
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2141
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2143
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2144
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2145
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2146
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2150
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2151
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2152
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2153
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2156
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2158
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2185
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2186
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2187
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2188
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2189
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2190
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2191
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2192
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2195
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P
View
5819
33364535
S567A
P
View
5820
33364535
I511V
P
View
5821
33364535
V521L
P
View
5822
9862871
V508L
P
View
5823
9862871
L515M
P
View
5824
9862871
P512L
P
View
5825
9862871
T519S
P
View
5826
9862871
I522L
P
View
5827
9862871
R577T
P
View
5828
9862871
Y580N
P
View
5829
9862871
E598D
P
View
Contents
Description
Table Description Column Note
D
Drugs mentioned in the relevant literature.
G
Genotypes/subtypes mentioned in the relevant literature.
R
Reference genomes mentioned in the relevant literature.
S
Viral sequences mentioned in the relevant literature.
C
Geographical distribution of the source mentioned in the relevant literature.
CI
Clinical information is available in the relevant literature.
I
This mutation is related to the immune escape.