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Mutation Information
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Mutation Site
|
L180M |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
22728692
|
|
Disease
|
Chronic hepatitis B
|
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Published Year
|
2012 |
|
Journal
|
Antiviral therapy |
|
Title
|
Lamivudine plus adefovir or telbivudine plus adefovir for chronic hepatitis B patients with suboptimal response to adefovir. |
|
Author
|
Chen EQ,Zhou TY,Bai L,Wang JR,Yan LB,Liang LB,Tang H |
|
Evidence
|
After 12-month treatment, 8.1% (3/37) of patients in group A and 5.7% (2/35) of patients in group B had VR; among patients in group A, two had rtM204V/I and rtL180M and one had rtN236T, whereas the two patients in group B had rtM204I+rtL180M.
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HBV Mutation Detail Information