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Mutation Information
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Mutation Site
|
A181T |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
Literature Information
|
PubMed PMID
|
32887289
|
|
Published Year
|
2020 |
|
Journal
|
International journal of molecular sciences |
|
Title
|
Hepatitis B Virus preS/S Truncation Mutant rtM204I/sW196* Increases Carcinogenesis through Deregulated HIF1A, MGST2, and TGFbi. |
|
Author
|
Lai MW,Liang KH,Yeh CT |
|
Evidence
|
Some of these mutants introduce premature stop codons in the overlapping surface (s) gene, including rtA181T/sW172*, which has been shown to enhance oncogenicity.
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HBV Mutation Detail Information