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Mutation Information
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Mutation Site
|
L180M |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Relevant Drug
|
adefovir (ADV);lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
20549958
|
|
Disease
|
HBV-HCV coinfection
|
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Published Year
|
2010 |
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Journal
|
Mikrobiyoloji bulteni |
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Title
|
[Genotype distribution of chronic hepatitis B and hepatitis C patients and investigation of the resistance patterns in hepatitis B cases]. |
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Author
|
Kalayci R,Altindiş M,Gülamber G,Demirtürk N,Akcan Y,Demirdal T |
|
Evidence
|
Various mutations were detected in 34.1% (15/44) of CHB patients and these were identified as M2041 (n = 6), Q215S (n = 2), L801 + M2041 (n = 1), L80V + M2041 (n = 1), Q215S + M2041 (n = 1) and M2041 + L180M (n = 1) mutations responsible for LAM resistance; V214A (n = 1) and A181T + N236T (n = 1) mutations responsible for adefovir (ADV) resistance, and V84M + V173L (n = 1) mutation responsible for ADV + LAM resistance.
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HBV Mutation Detail Information