HBV Mutation Detail Information

> A181V Search Result


Mutation Information
Mutation Site A181V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype C
Relevant Drug adefovir (ADV)
Country China
Literature Information
PubMed PMID 24992206
Disease Chronic hepatitis B
Published Year 2015
Journal Antiviral therapy
Title Investigation into drug-resistant mutations of HBV from 845 nucleoside/nucleotide analogue-naive Chinese patients with chronic HBV infection.
Author Li X,Liu Y,Zhao P,Wang Y,Chen L,Xin S,Zhang XX,Xu D
Evidence RESULTS: Drug-resistant mutations were detected in 2.01% (17/845) of the patients by direct sequencing, including 15 with lamivudine-resistant mutations (rtM204V, rtM204I), one with adefovir-resistant mutation (rtA181V), and one with both lamivudine- and adefovir-resistant mutations (rtA181V, rtM204I).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation