|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM);famciclovir (FCV) |
|
Country
|
the US |
Literature Information
|
PubMed PMID
|
12780567
|
|
Disease
|
HBV infection
|
|
Published Year
|
2003 |
|
Journal
|
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons |
|
Title
|
Characterization of hepatitis B virus surface antigen and polymerase mutations in liver transplant recipients pre- and post-transplant. |
|
Author
|
Germer JJ,Charlton MR,Ishitani MB,Forehand CD,Patel R |
|
Evidence
|
Significant viral polymerase mutations (rtL180M and rtM204I/V) also emerged in all of these patients following treatment with lamivudine and/or famciclovir.
|
|
|
HBV Mutation Detail Information