|
Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B |
|
Relevant Drug
|
Adefovir(ADV) |
|
Country
|
Taiwan(China) |
Literature Information
|
PubMed PMID
|
17400303
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2007 |
|
Journal
|
Antiviral research |
|
Title
|
Adefovir dipivoxil treatment of lamivudine-resistant chronic hepatitis B. |
|
Author
|
Dai CY,Chuang WL,Hsieh MY,Lee LP,Huang JF,Hou NJ,Lin ZY,Chen SC,Hsieh MY,Wang LY,Tsai JF,Chang WY,Yu ML |
|
Evidence
|
The rtN236T, rtA181V/T and rtI233V were not identified before ADV therapy and the genotypic mutation of rtN236T was detected in one (3.4%) patient.
|
|
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HBV Mutation Detail Information