|
Mutation Information
|
Mutation Site
|
M204T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Country
|
Australia |
Literature Information
|
PubMed PMID
|
24329944
|
|
Disease
|
HBV infection
|
|
Published Year
|
2014 |
|
Journal
|
Journal of viral hepatitis |
|
Title
|
Short duration of lamivudine for the prevention of hepatitis B virus transmission in pregnancy: lack of potency and selection of resistance mutations. |
|
Author
|
Ayres A,Yuen L,Jackson KM,Manoharan S,Glass A,Maley M,Yoo W,Hong SP,Kim SO,Luciani F,Bowden DS,Bayliss J,Levy MT,Locarnini SA |
|
Evidence
|
These variants increased significantly by T2. Pat13 was infected with an HBV variant with an rtM204T change, which in vitro phenotype studies have previously shown to be replication defective and LMV sensitive
|
|
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HBV Mutation Detail Information