|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
A |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Brazil |
Literature Information
|
PubMed PMID
|
24165277
|
|
Disease
|
HBV infection
|
|
Published Year
|
2013 |
|
Journal
|
Virology journal |
|
Title
|
Detection of lamivudine-resistant variants and mutations related to reduced antigenicity of HBsAg in individuals from the cities of Santos and São Paulo, Brazil. |
|
Author
|
Mantovani N,Cicero M,Santana LC,Silveira C,do Carmo EP,Abrão PR,Diaz RS,Caseiro MM,Komninakis SV |
|
Evidence
|
We were able to detect one sample with the resistance mutation to lamivudine rtM204V + rtL180M (2.94%), which was found in a volunteer blood donor that has never used antiviral drugs.
|
|
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HBV Mutation Detail Information