HBV Mutation Detail Information

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Mutation Information

Mutation Site	A181V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	lamivudine (LAM)
Country	USA

Literature Information

PubMed PMID	23114756
Clinical information	Yes
Disease	HBV infection
Published Year	2013
Journal	Antimicrobial agents and chemotherapy
Title	Low-level persistence of drug resistance mutations in hepatitis B virus-infected subjects with a past history of Lamivudine treatment.
Author	Margeridon-Thermet S,Svarovskaia ES,Babrzadeh F,Martin R,Liu TF,Pacold M,Reuman EC,Holmes SP,Borroto-Esoda K,Shafer RW
Evidence	HBV NRTI resistance mutations were defined as rtL80I/V, rtI169T, rtV173L, rtL180M, rtA181T/V, rtT184S/A/I/L/F/G, rtS202G/I, rtM204I/V/S, rtN236T, and rtM250V (1, 2).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation