HBV Mutation Detail Information

> L180C Search Result


Mutation Information
Mutation Site L180C
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.M204I+rt.L180C
Relevant Drug lamivudine (LAM)
Literature Information
PubMed PMID 15980328
Disease Chronic hepatitis B
Published Year 2005
Journal Antimicrobial agents and chemotherapy
Title Emergence of a novel mutation in the FLLA region of hepatitis B virus during lamivudine therapy.
Author Pai SB,Bozdayi AM,Pai RB,Beker T,Sarioglu M,Turkyilmaz AR,Grier J,Yurdaydin C,Schinazi RF
Evidence The mutant had a rtL180C/M204I genotype and was detected after 2 years of therapy with lamivudine.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation