Mutation Information
Mutation Site
|
D828A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
P |
Genotype/Subtype
|
C |
Literature Information
PubMed PMID
|
33803998
|
Published Year
|
2021 |
Journal
|
Microorganisms |
Title
|
rt269I Type of Hepatitis B Virus (HBV) Polymerase versus rt269L Is More Prone to Mutations within HBV Genome in Chronic Patients Infected with Genotype C2: Evidence from Analysis of Full HBV Genotype C2 Genome. |
Author
|
Jeong H,Kim DH,Choi YM,Choi H,Kim D,Kim BJ |
Evidence
|
We found a total of seven types of signature NS mutations in the Pol region (three types in RT, one type in the terminal protein (TP) region, two types in the spacer region and one type in the RNaseH region), of which all seven (rtN139K/H, rtM204I/V and rtI224V in RT, D16A/E/N/V in TP, S314P and F321L in Spacer and D828A/V in the RNaseH region) were rt269I signature types.
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