|
Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.N236T+rt.A181V |
|
Relevant Drug
|
lamivudine (LAM);adefovir dipivoxil (ADV) |
|
Country
|
Italy |
Literature Information
|
PubMed PMID
|
25742145
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2015 |
|
Journal
|
The new microbiologica |
|
Title
|
Clinical course of chronic hepatitis B patients receiving nucleos(t)ide analogues after virological breakthrough during monotherapy with lamivudine. |
|
Author
|
De Francesco MA,Gargiulo F,Spinetti A,Zaltron S,Giagulli C,Caccuri F,Castelli F,Caruso A |
|
Evidence
|
Mutations associated to ADV resistance were: Q215S, A181V, N236T and V214E.
|
|
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HBV Mutation Detail Information