|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.T184F+rt.L180M;rt.M204V+rt.T184F+rt.L180M+rt.V173M |
|
Genotype/Subtype
|
C |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
26889227
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2016 |
|
Journal
|
Experimental and therapeutic medicine |
|
Title
|
Evolution of entecavir-resistant hepatitis B virus during entecavir and adefovir dipivoxil combination therapy. |
|
Author
|
Wang Y,Liu S,Chen YU,Zheng S,Zhou LI,Hua T,Sui S,Lu F,Duan Z |
|
Evidence
|
In patient A, the rtL180M, rtS202G and rtM204V mutant variants were detected using pyrosequencing prior to virological breakthrough.
|
|
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HBV Mutation Detail Information