HBV Mutation Detail Information

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Mutation Information
Mutation Site M204V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype C
Relevant Drug adefovir (ADV);adefovir dipivoxil (ADV)
Literature Information
PubMed PMID 19323782
Disease Chronic hepatitis B
Published Year 2009
Journal Liver international : official journal of the International Association for the Study of the Liver
Title Hepatitis B virus with the rtL80V/I mutation is associated with a poor response to adefovir dipivoxil therapy.
Author Lee YS,Chung YH,Kim JA,Kim SE,Shin JW,Kim KM,Lim YS,Park NH,Lee HC,Lee YS,Suh DJ
Evidence BACKGROUND/AIMS: Lamivudine (LAM) resistance is frequently associated with various types of genomic changes in hepatitis B virus (HBV)-DNA including YMDD mutations (rtM204V/I).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation