Mutation Information
Mutation Site
|
M204V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
C |
Relevant Drug
|
adefovir (ADV);adefovir dipivoxil (ADV) |
Literature Information
PubMed PMID
|
19323782
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2009 |
Journal
|
Liver international : official journal of the International Association for the Study of the Liver |
Title
|
Hepatitis B virus with the rtL80V/I mutation is associated with a poor response to adefovir dipivoxil therapy. |
Author
|
Lee YS,Chung YH,Kim JA,Kim SE,Shin JW,Kim KM,Lim YS,Park NH,Lee HC,Lee YS,Suh DJ |
Evidence
|
BACKGROUND/AIMS: Lamivudine (LAM) resistance is frequently associated with various types of genomic changes in hepatitis B virus (HBV)-DNA including YMDD mutations (rtM204V/I).
|
|
|