HBV Mutation Detail Information

> M204I Search Result


Mutation Information
Mutation Site M204I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype C
Relevant Drug lamivudine (LAM)
Country Korea
Literature Information
PubMed PMID 20332649
Disease Chronic hepatitis B
Published Year 2010
Journal Intervirology
Title Response to adefovir depends on mutation patterns in precore region, basal core promoter and reverse transcriptase, and on-treatment responses in Lamivudine-resistant chronic hepatitis B patients.
Author Song BC,Cui XJ,Shin JW,Park NH,Cho YK,Song HJ,Hyun S,Jeong SU,Choi EK,Kim HU
Evidence RtM204I, rtM204V, rtM204I/V mutations and the wild type were found in 36 patients (54.5%), 25 patients (37.9%), 4 patients (6.1%) and 1 patient (1.5%), respectively, prior to adefovir therapy.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation