Mutation Information
Mutation Site
|
M204I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
C |
Relevant Drug
|
lamivudine (LAM) |
Country
|
Korea |
Literature Information
PubMed PMID
|
20332649
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2010 |
Journal
|
Intervirology |
Title
|
Response to adefovir depends on mutation patterns in precore region, basal core promoter and reverse transcriptase, and on-treatment responses in Lamivudine-resistant chronic hepatitis B patients. |
Author
|
Song BC,Cui XJ,Shin JW,Park NH,Cho YK,Song HJ,Hyun S,Jeong SU,Choi EK,Kim HU |
Evidence
|
RtM204I, rtM204V, rtM204I/V mutations and the wild type were found in 36 patients (54.5%), 25 patients (37.9%), 4 patients (6.1%) and 1 patient (1.5%), respectively, prior to adefovir therapy.
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