HBV Mutation Detail Information

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Mutation Information
Mutation Site K212T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.M250L+rt.K212T
Relevant Drug adefovir (ADV);adefovir dipivoxil (ADV)
Country China
Literature Information
PubMed PMID 19302908
Disease Chronic hepatitis B
Published Year 2009
Journal Clinical therapeutics
Title Evolution of hepatitis B virus polymerase mutations in a patient with HBeAg-positive chronic hepatitis B virus treated with sequential monotherapy and add-on nucleoside/nucleotide analogues.
Author Wang F,Wang H,Shen H,Meng C,Weng X,Zhang W
Evidence A total of 20.6% (7/34) of the clones harbored the rtK212T + rtM250L mutation, and rtA181V was found in 2.9% (1/34) of the clones.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation