Mutation Information
Mutation Site
|
S331C |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
P |
Combined Mutation
|
p.S331C+rt.A181T |
Genotype/Subtype
|
C |
Country
|
Japan |
Literature Information
PubMed PMID
|
16982790
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2006 |
Journal
|
Antimicrobial agents and chemotherapy |
Title
|
Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif. |
Author
|
Yatsuji H,Noguchi C,Hiraga N,Mori N,Tsuge M,Imamura M,Takahashi S,Iwao E,Fujimoto Y,Ochi H,Abe H,Maekawa T,Tateno C,Yoshizato K,Suzuki F,Kumada H,Chayama K |
Evidence
|
The detected nucleotide substitution was accompanied by the emergence of an additional nucleotide substitution that induced amino acid change (S331C) in the spacer domain.
|
|
|