|
Mutation Information
|
Mutation Site
|
T184G |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
entecavir (ETV);adefovir (ADV) |
Literature Information
|
PubMed PMID
|
20169198
|
|
Published Year
|
2010 |
|
Journal
|
PloS one |
|
Title
|
Mechanistic characterization and molecular modeling of hepatitis B virus polymerase resistance to entecavir. |
|
Author
|
Walsh AW,Langley DR,Colonno RJ,Tenney DJ |
|
Evidence
|
A previously described isolate containing both T184G and S202I substitutions displayed the highest ETVr levels, suggesting that multiple ETVr changes in a LVDr background may have additive or synergistic effects.
|
|
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HBV Mutation Detail Information