HBV Mutation Detail Information

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Mutation Information

Mutation Site	M250V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Country	China

Literature Information

PubMed PMID	29119303
Disease	HBV infection
Published Year	2018
Journal	Virus genes
Title	Evolution of drug-resistant mutations in HBV genomes in patients with treatment failure during the past seven years (2010-2016).
Author	Zhang HY,Liu LG,Ye CY,Chen CH,Hang SX,Zhu Z,Shen HY,Huang ZY,Chen WY,Xue Y
Evidence	Among the primary NA-resistance mutations, rtM204I (13.44%, 545/4055) occurred more frequently, followed by rtM204V (11.83%, 480/4055), rtN236T (5.97%, 242/4055), rtA181T (3.58%, 145/4055), and rtA181V (3.13%, 127/4055). Other mutations, such as rtI169T and rtM250V, were scarce (Fig. 1a).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation