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HBV Mutation Detail Information

> M552V Search Result


Mutation Information
Mutation Site M552V
Mutation Type Amino acid level
Gene/Protein/Region Type P
Relevant Drug lamivudine (LAM)
Literature Information
PubMed PMID 11584376
Disease Chronic hepatitis B
Published Year 2001
Journal Hepatology (Baltimore, Md.)
Title Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy.
Author Yuen MF,Sablon E,Hui CK,Yuan HJ,Decraemer H,Lai CL
Evidence Patients with HBV DNA breakthroughs had higher percentages of YMDD variants without the presence of wild-type YMDD compared with patients without HBV DNA breakthrough (25.6% vs. 9%, P =.007 for single M552I variant; 20.9% vs. 8.1%, P =.026 for single M552V variant; 30.2% vs. 9.9%, P =.004 for M552I/M552V variants).
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation