|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Iran |
Literature Information
|
PubMed PMID
|
21671883
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2011 |
|
Journal
|
Current HIV research |
|
Title
|
Detection of hepatitis B virus variants in HBV monoinfected and HBV/HIV coinfected Iranian patients under lamivudine treatment. |
|
Author
|
Aghasadeghi MR,Bahramali G,Sadat SM,Farahani A,Mohraz M,Davar Siadat S,Mostafavi E,Memarnejadian A,Ardestani MS,Vahabpour R,Saraji AA,Delbaz SA |
|
Evidence
|
While no resistance mutation was detected in HBV/HIV coinfected cohort, LAM-resistance mutations (rtM204I/V in YMDD and rtL180M in FLLA polymerase motifs) were identified in 30% (9 out of 30) and 16.
|
|
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HBV Mutation Detail Information