Mutation Information
Mutation Site
|
Q215S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
lamivudine (LAM) |
Literature Information
PubMed PMID
|
16549970
|
Disease
|
HBV-HIV coinfection
|
Published Year
|
2006 |
Journal
|
AIDS (London, England) |
Title
|
Characteristics of drug resistant HBV in an international collaborative study of HIV-HBV-infected individuals on extended lamivudine therapy. |
Author
|
Matthews GV,Bartholomeusz A,Locarnini S,Ayres A,Sasaduesz J,Seaberg E,Cooper DA,Lewin S,Dore GJ,Thio CL |
Evidence
|
However, one patient who had received > 48 months of 3TC (71 months) had a mutation at rtQ215S, which is associated with ADV and 3TC resistance in vitro
|
|
|