Mutation Information
Mutation Site
|
S202V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
D |
Relevant Drug
|
lamivudine (LAM);entecavir (ETV) |
Literature Information
PubMed PMID
|
20169198
|
Published Year
|
2010 |
Journal
|
PloS one |
Title
|
Mechanistic characterization and molecular modeling of hepatitis B virus polymerase resistance to entecavir. |
Author
|
Walsh AW,Langley DR,Colonno RJ,Tenney DJ |
Evidence
|
The results of comprehensive phenotypic analysis of substitutions at positions S202 [8] indicated that S202A/G/C/T/V/N replicated well and S202 I/F/Y replicated poorly, but that other S202 changes did not replicate.
|
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