|
Mutation Information
|
Mutation Site
|
V555I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Relevant Drug
|
famciclovir (FCV) |
Literature Information
|
PubMed PMID
|
10365797
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
1999 |
|
Journal
|
Journal of hepatology |
|
Title
|
Absence of mutations in the YMDD motif/B region of the hepatitis B virus polymerase in famciclovir therapy failure. |
|
Author
|
Günther S,von Breunig F,Santantonio T,Jung MC,Gaeta GB,Fischer L,Sterneck M,Will H |
|
Evidence
|
Lamivudine rescue therapy initiated in four patients, including a patient infected with YMDD(555-V-->I) variants, efficiently reduced viremia.
|
|
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HBV Mutation Detail Information