|
Mutation Information
|
Mutation Site
|
T184L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.A200V+rt.T184L+rt.L180M;rt.M204V+rt.A200V+rt.T184L |
|
Viral Reference
|
AB026813
|
|
Relevant Drug
|
entecavir (ETV);tenofovir (TDF) |
|
Country
|
china |
Literature Information
|
PubMed PMID
|
31498528
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2020 |
|
Journal
|
Liver international : official journal of the International Association for the Study of the Liver |
|
Title
|
Entecavir resistance mutations rtL180M/T184L/M204V combined with rtA200V lead to tenofovir resistance. |
|
Author
|
Jiang D,Wang J,Zhao X,Li Y,Zhang Q,Song C,Zeng H,Wang X |
|
Evidence
|
Entecavir resistance mutations rtL180M/T184L/M204V combined with rtA200V lead to tenofovir resistance.
|
|
|
HBV Mutation Detail Information