HBV Mutation Detail Information

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Mutation Information

Mutation Site	L528M
Mutation Type	Amino acid level
Gene/Protein/Region Type	P
Genotype/Subtype	A

Literature Information

PubMed PMID	14756274
Disease	Chronic hepatitis B; Hepatocellular carcinoma
Published Year	2003
Journal	Clinical transplantation
Title	Efficacy of combined lamivudine and adefovir dipivoxil treatment for severe HBV graft reinfection after living donor liver transplantation.
Author	Beckebaum S,Malagó M,Dirsch O,Cicinnati VR,Trippler M,Lampertico P,Lama N,Treichel U,Gerken G,Broelsch CE
Evidence	Hepatitis B virus sequence analysis revealed several mutations in the polymerase gene (L528M, M552I, M552V) as well as in the surface gene region encoding the immunogenic major hydrophilic loop of the small surface protein (G130N, M133T, D144G).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation