HBV Mutation Detail Information

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Mutation Information

Literature Information

PubMed PMID	9862871
Disease	Chronic hepatitis B
Published Year	1999
Journal	Hepatology (Baltimore, Md.)
Title	Transient selection of a hepatitis B virus polymerase gene mutant associated with a decreased replication capacity and famciclovir resistance.
Author	Pichoud C,Seignères B,Wang Z,Trépo C,Zoulim F
Evidence	Two mutations, V508L and L515M, were foundin domain B of the viral polymerase at the time of the viralbreakthrough without any sequence change in the YMDDmotif

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Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)