HBV Mutation Detail Information

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Mutation Information
Mutation Site S202I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Country China
Literature Information
PubMed PMID 31189581
Disease Chronic hepatitis B; HBV associated liver disease; HBV infection
Published Year 2019
Journal Journal of clinical microbiology
Title Characterization and Clinical Significance of Natural Variability in Hepatitis B Virus Reverse Transcriptase in Treatment-Naive Chinese Patients by Sanger Sequencing and Next-Generation Sequencing.
Author Fu Y,Zeng Y,Chen T,Chen H,Lin N,Lin J,Liu X,Huang E,Wu S,Wu S,Xu S,Wang L,Ou Q
Evidence The classical drug resistance mutations were not found by Sanger sequencing, while S202C/G/I (0.92% to ∼3.45%), M204I/V/S (0.90% to ∼8.32%), N236T (1.16% to ∼3.63%), and M250I/L/V (0.90% to ∼1.83%) were found at a low rate by NGS.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation