HBV Mutation Detail Information

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Mutation Information
Mutation Site M204V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.M204V+rt.L180M
Relevant Drug lamivudine (LAM)
Country Brazil
Literature Information
PubMed PMID 19817965
Disease Chronic hepatitis B
Published Year 2010
Journal Journal of gastroenterology and hepatology
Title Occult hepatitis B virus infection and lamivudine-resistant mutations in isolates from renal patients undergoing hemodialysis.
Author Motta JS,Mello FC,Lago BV,Perez RM,Gomes SA,Figueiredo FF
Evidence Four of these six HBV isolates contained mutations associated with lamivudine resistance in the DNA polymerase (two with L180M/M204V and two with rt173V/180M/204V) and a specific substitution (Y100C) in the HBV small surface protein.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation