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Mutation Information
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Mutation Site
|
M204V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.L180M |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
20944991
|
|
Published Year
|
2010 |
|
Journal
|
Memorias do Instituto Oswaldo Cruz |
|
Title
|
Hepatitis B genotype G and high frequency of lamivudine-resistance mutations among human immunodeficiency virus/hepatitis B virus co-infected patients in Brazil. |
|
Author
|
Silva AC,Spina AM,Lemos MF,Oba IT,Guastini Cde F,Gomes-Gouvêa MS,Pinho JR,Mendes-Correa MC |
|
Evidence
|
In 10 patients with viremia, LAM-resistance mutations in the polymerase gene (rtL180M + rtM204V and rtV173L + rtL180M + rtM204V) were found, accompanied by changes in the envelope gene (sI195M, sW196L and sI195M/sE164D).
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HBV Mutation Detail Information