HBV Mutation Detail Information

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Mutation Information

Mutation Site	I169T
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	A
Country	Spain

Literature Information

PubMed PMID	22666402
Disease	Chronic hepatitis B
Published Year	2012
Journal	PloS one
Title	Ultra-deep pyrosequencing detects conserved genomic sites and quantifies linkage of drug-resistant amino acid changes in the hepatitis B virus genome.
Author	Rodriguez-Frías F,Tabernero D,Quer J,Esteban JI,Ortega I,Domingo E,Cubero M,Camós S,Ferrer-Costa C,Sánchez A,Jardí R,Schaper M,Homs M,Garcia-Cehic D,Guardia J,Esteban R,Buti M
Evidence	The 10 most variable substitutions (highest SD value), rtL180M, rtM204V, rtS202G, rtV207I, rtA181T, rtV173L, rtI169T, rtV191I, rtM204I and rtT184A, are known to be associated with NA resistance.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation