Mutation Information
Mutation Site
|
M204V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Combined Mutation
|
rt.M204V+rt.L180M;rt.M204V+rt.L180M+rt.L173V |
Genotype/Subtype
|
A;D |
Relevant Drug
|
lamivudine (LAM) |
Country
|
Spain |
Literature Information
PubMed PMID
|
17224847
|
Disease
|
HBV-HIV coinfection
|
Published Year
|
2007 |
Journal
|
Journal of acquired immune deficiency syndromes (1999) |
Title
|
Hepatitis B virus genotypes and lamivudine resistance mutations in HIV/hepatitis B virus-coinfected patients. |
Author
|
Ramos B,Núñez M,Martín-Carbonero L,Sheldon J,Rios P,Labarga P,Romero M,Barreiro P,García-Samaniego J,Soriano V |
Evidence
|
The dual L180M + M204V/I mutant was the predominant resistance pattern, although a triple rt173V + 180M + 204V, which acts as a vaccine escape mutant, was found in 1 individual.
|
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