HBV Mutation Detail Information

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Mutation Information

Mutation Site	L80I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Country	North USA; Europe; and New Zealand

Literature Information

PubMed PMID	24368224
Disease	Chronic hepatitis B
Published Year	2014
Journal	Gastroenterology
Title	Randomized comparison of tenofovir disoproxil fumarate vs emtricitabine and tenofovir disoproxil fumarate in patients with lamivudine-resistant chronic hepatitis B.
Author	Fung S,Kwan P,Fabri M,Horban A,Pelemis M,Hann HW,Gurel S,Caruntu FA,Flaherty JF,Massetto B,Dinh P,Corsa A,Subramanian GM,McHutchison JG,Husa P,Gane E
Evidence	INNO-LiPA analysis at screening revealed rtM204V/I and rtL180M mutations present in 99% and 65% of patients, respectively; in addition, 47% and 7% of patients overall were found to harbor rtL80V/I and rtV173L mutations, respectively (Supplementary Table 1).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation