|
Mutation Information
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Mutation Site
|
M552I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
10377169
|
|
Published Year
|
1999 |
|
Journal
|
The Journal of clinical investigation |
|
Title
|
Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors. |
|
Author
|
Ono-Nita SK,Kato N,Shiratori Y,Lan KH,Yoshida H,Carrilho FJ,Omata M |
|
Evidence
|
In this study, susceptibility of wild-type and lamivudine-resistant HBV M552I, M552V, and L528M/M552V mutants to other reverse transcriptase inhibitors was investigated by transient transfection of full-length HBV DNA intoHuman hepatoma cells.
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HBV Mutation Detail Information