HBV Mutation Detail Information

> L80I Search Result

Mutation Information

Mutation Site	L80I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.M204I+rt.S202C+rt.T184L+rt.L180M+rt.L80I+rt.A194T;rt.M204I+rt.S202G+rt.T184L+rt.L180M+rt.L80I+rt.A194T;rt.M204I+rt.A181T+rt.L80I+rt.A194T;rt.M204I+rt.L180M+rt.L80I+rt.D134E+rt.H126Y+rt.S106C;rt.M204I+rt.L180M+rt.L80I+rt.L269I+rt.D134E+rt.H126Y+rt.S106C
Relevant Drug	lamivudine (LAM);entecavir (ETV);adefovir dipivoxil (ADV);tenofovir (TFV);tenofovir alafenamide (TAF)

Literature Information

PubMed PMID	32894807
Disease	Chronic hepatitis B
Published Year	2021
Journal	Journal of viral hepatitis
Title	Characterization of Hepatitis B virus polymerase mutations A194T and CYEI and tenofovir disoproxil fumarate or tenofovir alafenamide resistance.
Author	Liu Y,Chang S,Martin R,Flaherty J,Mo H,Feierbach B
Evidence	TABLE 3

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation