Mutation Information
Mutation Site
|
M204V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
lamivudine (LAM) |
Literature Information
PubMed PMID
|
15655050
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2005 |
Journal
|
Journal of viral hepatitis |
Title
|
Activity of adefovir dipivoxil against all patterns of lamivudine-resistant hepatitis B viruses in patients. |
Author
|
Westland CE,Yang H,Delaney WE 4th,Wulfsohn M,Lama N,Gibbs CS,Miller MD,Fry J,Brosgart CL,Schiff ER,Xiong S |
Evidence
|
Four major patterns of lamivudine-resistant HBV were identified: rtL180M + rtM204V (60%), rtV173L + rtL180M + rtM204V (19%), rtM204I (9%) and rtL180M + rtM204I (9%).
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