Mutation Information
Mutation Site
|
N236T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
B;C |
Viral Reference
|
Y1855;
DQ448619.1 |
Relevant Drug
|
adefovir (ADV) |
Country
|
China |
Literature Information
PubMed PMID
|
22138714
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2012 |
Journal
|
Antiviral research |
Title
|
Prevalence, virology and antiviral drugs susceptibility of hepatitis B virus rtN238H polymerase mutation from 1865 Chinese patients with chronic hepatitis B. |
Author
|
Zhong Y,Lv J,Li J,Xing X,Zhu H,Su H,Chen L,Zhou X |
Evidence
|
These were compared to WT as well as ADV- (rtN236T) and LAM resistant (rtM204I or rtL180M + rtM204V) constructs.
|
|
|