|
Mutation Information
|
Mutation Site
|
D553V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
Literature Information
|
PubMed PMID
|
10827158
|
|
Disease
|
HBV infection
|
|
Published Year
|
2000 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Clearance of the original hepatitis B virus YMDD-motif mutants with emergence of distinct lamivudine-resistant mutants during prolonged lamivudine therapy. |
|
Author
|
Yeh CT,Chien RN,Chu CM,Liaw YF |
|
Evidence
|
Other mutants harboring mutations in domain B and C ofHBV polymerase sequence were as followed: L528M/A529T,L528M/Y551N, L528M/M552E, L528M/D553V, L528M/L527P, L528R/A529T, Q530-to-Stop, M552Q, and L527P.
|
|
|
HBV Mutation Detail Information