HBV Mutation Detail Information

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Mutation Information

Mutation Site	L180M
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	C
Relevant Drug	lamivudine (LAM);entecavir (ETV);tenofovir (TDF)
Country	Korea

Literature Information

PubMed PMID	24836314
Disease	Chronic hepatitis B
Published Year	2014
Journal	Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Title	Viral evolutionary changes during tenofovir treatment in a chronic hepatitis B patient with sequential nucleos(t)ide therapy.
Author	Lee HW,Chang HY,Yang SY,Kim HJ
Evidence	A 54-year-old man diagnosed with HBeAg-positiveChronic hepatitis B(CHB) was treated with entecavir (ETV) 1mg/day following an initial unsuccessful lamivudine (LAM) treatment (rtL180M, rtM204V/I).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation