|
Mutation Information
|
Mutation Site
|
V173L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.S202I+rt.V191G+rt.Q182H+rt.L180M+rt.V173L+rt.V163P;rt.K266V+rt.R266V+rt.I266V+rt.Y257H+rt.Q215H+rt.V214A+rt.V207I+rt.I187L+rt.V173L+rt.L164M+rt.F122L;rt.E271H+rt.I266V+rt.S259T+rt.Y257W+rt.V253I+rt.F221Y+rt.M204V+rt.L180M+rt.V173L+rt.I163V+rt.R153W+rt.F151Y+rt.L145M+rt.V142D |
|
Genotype/Subtype
|
A;D |
|
Relevant Drug
|
lamivudine (LAM);tenofovir (TDF) |
|
Country
|
Rome |
Literature Information
|
PubMed PMID
|
19442845
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2009 |
|
Journal
|
Journal of virological methods |
|
Title
|
A sensitive direct sequencing assay based on nested PCR for the detection of HBV polymerase and surface glycoprotein mutations. |
|
Author
|
Vincenti D,Solmone M,Garbuglia AR,Iacomi F,Capobianchi MR |
|
Evidence
|
Table 1
|
|
|
HBV Mutation Detail Information