|
Mutation Information
|
Mutation Site
|
A181V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV) |
Literature Information
|
PubMed PMID
|
19195324
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2008 |
|
Journal
|
Antiviral therapy |
|
Title
|
Adefovir for chronic hepatitis B treatment: identification of virological markers linked to therapy response. |
|
Author
|
Rodriguez-Frias F,Jardi R,Schaper M,Buti M,Ferrer-Costa C,Tabernero D,Homs M,Esteban R |
|
Evidence
|
BACKGROUND: HBV variants rtA181V/T, rtN236T and rtl233V, which confer resistance to adefovir dipivoxil (ADV), are not detected in many non-responding patients.
|
|
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HBV Mutation Detail Information