Mutation Information
Mutation Site
|
N236T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
adefovir (ADV) |
Country
|
Spain |
Literature Information
PubMed PMID
|
17988612
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2007 |
Journal
|
Medicina clinica |
Title
|
[Adefovir dipivoxil compassionate use program in Spain: efficacy and resistance analysis]. |
Author
|
Buti M,Rodríguez Frías F,Calleja JL,Jardí R,Pons F,Crespo J,Casanovas T,Enríquez J,Carnicer F,Romero M,García Bengoechea M,Prieto M,García Samaniego J,Miras M,Pérez Roldán F,Rueda M,Esteban R |
Evidence
|
20% patients developed resistance to adefovir dipivoxil, and the most frequent detected mutations were: A181V, A181T and N236T.
|
|
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