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Mutation Information
|
Mutation Site
|
M250V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
26876337
|
|
Clinical information
|
Yes
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2016 |
|
Journal
|
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases |
|
Title
|
Prevalence of mutations in HBV DNA polymerase gene associated with nucleos(t)ide resistance in treatment-naive patients with Chronic Hepatitis B in Central China. |
|
Author
|
Zhao Y,Wu J,Sun L,Liu G,Li B,Zheng Y,Li X,Tao J |
|
Evidence
|
Mutations in HBV DNA polymerase were detected in 24 patients (8.9%) including rtM204I/V (n=6), rtN236T (n=5), rtM250V (n=2), rtL180M (n=2), rtT184G (n=1), rtM207I (n=1), rtS202I (n=1), rtM204V/I & rtL180M (n=5), and rtM204I & rtM250V (n=1).
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HBV Mutation Detail Information