|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
16618409
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2006 |
|
Journal
|
Gastroenterology |
|
Title
|
Predominance of hepatitis B virus YMDD mutants is prognostic of viral DNA breakthrough. |
|
Author
|
Lee CH,Kim SO,Byun KS,Moon MS,Kim EO,Yeon JE,Yoo W,Hong SP |
|
Evidence
|
RFMP exploits differences in molecular masses between wild-type and variant bases of rtM204V/I following PCR amplification of HBV DNA with a lower limit of detection being 100 copies/mL.
|
|
|
HBV Mutation Detail Information