HBV Mutation Detail Information

> L528M Search Result


Mutation Information
Mutation Site L528M
Mutation Type Amino acid level
Gene/Protein/Region Type P
Combined Mutation p.M552I+p.L528M
Relevant Drug lamivudine (LAM)
Literature Information
PubMed PMID 10996115
Disease Chronic hepatitis B
Published Year 2000
Journal Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Title In vivo dynamics and pathogenicity of wild-type and resistant Hepatitis B virus during long-term lamivudine monotherapy - a clinical note.
Author Zöllner B,Stoehr A,Plettenberg A,Feucht H,Schröter M,Schäfer P,Laufs R
Evidence Nineteen weeks later, the virus exhibited additional resistance-associated mutations (L528M and I552V).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation