HBV Mutation Detail Information

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Mutation Information
Mutation Site M204V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.M204V+rt.N236T
Relevant Drug lamivudine;telbivudine
Country China
Literature Information
PubMed PMID 33986897
Disease Chronic hepatitis B
Published Year 2021
Journal The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale
Title High Prevalence of Preexisting HBV Polymerase Mutations in Pregnant Women Does Not Limit the Antiviral Therapy Efficacy.
Author Wang J,Liu J,Yu Q,Jin L,Yao N,Yang Y,Yan T,Hu C,He Y,Zhao Y,Chen T,Zheng J
Evidence Results: Before TBV treatment, the complexity of HBV quasispecies of all subjects was 0.40 +- 0.09; 41.1% (30/73) and 53.4% (39/73) subjects had rtM204I/V and rtN236 T/A detected, respectively; and 9.6% (7/73) patients had more than 20% frequency mutation of rtM204I/V, which was also similar with high frequency of rtN236 T/A mutation (41.1% vs.

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Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation