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Mutation Information
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Mutation Site
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I169L |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Relevant Drug
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tenofovir (TDF);emtricitabine (FTC);efavirenz (EFV) |
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Country
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Gabon |
Literature Information
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PubMed PMID
|
29315352
|
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Disease
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HBV-HIV coinfection
|
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Published Year
|
2018 |
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Journal
|
PloS one |
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Title
|
Hepatitis B infection among HIV infected individuals in Gabon: Occult hepatitis B enhances HBV DNA prevalence. |
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Author
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Bivigou-Mboumba B,Amougou-Atsama M,Zoa-Assoumou S,M'boyis Kamdem H,Nzengui-Nzengui GF,Ndojyi-Mbiguino A,Njouom R,François-Souquière S |
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Evidence
|
The analysis of HBV strains for the S/Pol gene by the MRT online software showed that of the major RAMs, M204V/I was the most frequent (4/10, 40%), followed by its compensatory RAMs; L180M (3/10, 30%) and V173L (2/10, 20%). The MRT revealed I169L mutation in one patient (Fig 4, Table 4).
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HBV Mutation Detail Information