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Mutation Information
|
Mutation Site
|
L132Q |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
D00630;
M54923;
HPBAYW |
|
Country
|
Greek |
Literature Information
|
PubMed PMID
|
16789016
|
|
Disease
|
HBV infection
|
|
Published Year
|
2006 |
|
Journal
|
Journal of medical virology |
|
Title
|
Detection of a hepatitis B surface antigen variant emerging in a patient with chronic lymphocytic leukaemia treated with fludarabine. |
|
Author
|
Alexopoulou A,Dourakis SP,Pandelidaki H,Archimandritis AJ,Karayiannis P |
|
Evidence
|
Two of the mutations in the a determinant region,affecting codons 122 and 130, led to amino-acidsubstitutions in the A–B interdomain region of theoverlapping polymerase gene (rtL132Q, rtR138K).
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HBV Mutation Detail Information