HBV Mutation Detail Information

> A181A Search Result

Mutation Information

Mutation Site	A181A
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	C
Relevant Drug	lamivudine (LAM)
Country	Japan

Literature Information

PubMed PMID	21503906
Disease	Chronic hepatitis B
Published Year	2011
Journal	Journal of medical virology
Title	Clinical course and predictive factors of virological response in long-term lamivudine plus adefovir dipivoxil combination therapy for lamivudine-resistant chronic hepatitis B patients.
Author	Aizawa M,Tsubota A,Fujise K,Tatsuzawa K,Kono M,Hoshina S,Tajiri H
Evidence	Breakthrough hepatitis occurred in three patients without complete viral response and with poor response to the preceding LAM monotherapy, and rtA181A/V substitution was detected in one of the three patients.

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation